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C8 Study Results - Status Reports

August 7, 2012

Below is a link to a Status Report on C8 (PFOA) exposure and markers of kidney function in children and adolescents, submitted to the Wood County Court in Parkersburg, West Virginia on July 30, 2012 under the C8 Settlement. More detailed reports are being submitted to a peer-reviewed journal for publication. When accepted and published, details for accessing the publication will be provided here.

Status report: Exposure to perfluoroalkyl acids and markers of kidney function in children and adolescents

May 11, 2012

Below is a link to a Status Report on C8 (PFOA) level during pregnancy in mothers in the Mid-Ohio Valley and infections, obesity and clinical markers in their children, submitted to the Wood County Court in Parkersburg, West Virginia under the C8 Settlement. More detailed reports are being submitted to a peer-reviewed journal for publication. When accepted and published, details for accessing the publication will be provided here.

Status report: Infections, obesity and clinical markers in children in relation to C8 (PFOA) during pregnancy in mothers in the Mid-Ohio Valley

December 5, 2011

Below are links to three Status Reports submitted to the Wood County Court in Parkersburg, West Virginia under the C8 Settlement. The first is a report on changes in serum C8 and lipid changes. The second is an analysis of C8 and pregnancy-induced hypertension and preeclampsia. The third reports on C8 and occurence of thyroid disease in adults. More detailed reports are being submitted to peer-reviewed journals for publication. When they are accepted and published, details for accessing the publication will be provided here.

Status report: Changes in serum PFOA/PFOS and serum lipids between 2005 and 2010 in the Mid-Ohio Valley

Status report: Prospective study of reproductive health outcomes in the Mid-Ohio Valley

Status report: PFOA and adult thyroid disease in the Mid-Ohio Valley

September 23, 2011

Below is a link to a Status Report on C8 (PFOA) Exposure and Pregnancy Outcome based on Ohio and West Virginia Birth Records and Linkage to C8 Health Project Participants, submitted to the Wood County Court in Parkersburg, West Virginia under the C8 Settlement. A more detailed report is being submitted to a peer-reviewed journal for publication. When it is accepted and published, details for accessing the publication will be provided here.

Status report: C8 (PFOA) Exposure and Pregnancy Outcome based on Ohio and West Virginia Birth Records and Linkage to C8 Health Project Participants

August 18, 2011

Below is a link to a Status Report on Serum PFOA and Markers of Thyroid Function in Children in the Mid-Ohio Valley, submitted to the Wood County Court in Parkersburg, West Virginia under the C8 Settlement. A more detailed report is being submitted to a peer-reviewed journal for publication. When it is accepted and published, details for accessing the publication will be provided here.

Status report: Serum PFOA and Markers of Thyroid Function in Children in the Mid-Ohio Valley

July 19, 2011

Below are links to three Status Reports submitted to the Wood County Court in Parkersburg, West Virginia under the C8 Settlement. The first is a report on C8 and liver function markers. The second details the mortality rate of workers employed at the DuPont Washington Works plant. The third is an analysis of C8 and pregnancy outcomes among women in the C8 Health Project. More detailed reports are being submitted to peer-reviewed journals for publication. When they are accepted and published, details for accessing the publication will be provided here.

Status report: Serum PFOA and liver function markers in the blood of adults in the Mid-Ohio Valley

Status report: The mortality of DuPont workers in relation to exposure to PFOA (C8)

Status report: PFOA (C8) exposure and pregnancy outcome among participants in the C8 Health Project

February 2, 2011

Below is a link to a Status Report on C8 and Attention Deficit/Attention Deficit Hyperactivity Disorder and Learning Disorder among children, submitted to the Wood County Court in Parkersburg, West Virginia under the C8 Settlement. A more detailed report is being submitted to a peer-reviewed journal for publication. When it is accepted and published, details for accessing the publication will be provided here.

Status report: Association of perfluorinated compounds with Attention Deficit/Attention Deficit Hyperactivity Disorder and Learning Disorder among children aged 5-18 years with elevated community exposure to PFOA

September 30, 2010

Below is a link to a Status Report on C8 and patterns of age of puberty, submitted to the Wood County Court in Parkersburg, West Virginia under the C8 Settlement. Right-click on the title and save or open the document (pdf format).

Status report: Patterns of age of puberty among children in the Mid-Ohio Valley in relation to Perfluorooctanoic Acid (PFOA) and Perfluorooctane Sulfonate (PFOS)

October 30, 2009

Below is a link to a Status Report on C8 and cholesterol levels in children, submitted to the Wood County Court in Parkersburg, West Virginia under the C8 Settlement. A more detailed report is being submitted to a peer-reviewed journal for publication. When it is accepted and published, details for accessing them will be provided here. Right-click on the title and save or open the document (pdf format). This report arises from a collaboration between West Virginia University and the Science Panel on analyses of data collected in the C8 Health Project

Status report: Association of perfluorooctanic acid (C8/PFOA) and perfluoroctanesulfonate (PFOS) with lipids among children in the Mid-Ohio Valley

March 26, 2009

Below are links to two more status reports which have been filed with the Wood Country Court in WV. The first report concerns the time required for C8 to be removed from the body after exposure stops. This study is based on 200 people in the Lubeck and Little Hocking water districts, whose blood level of C8 was measured over a year period before and after the installation of water filters which have removed C8 from public drinking water. The second evaluates several indicators of the health of pregnancies among women who participated in the C8 Health Project and had a pregnancy shortly before enrollment. The reports are concise summaries of some results of this work. More detailed reports are being submitted to peer-reviewed journals for publication. Right-click on the title and save or open the document (pdf format).

Status report: Residents' PFOA serum concentrations before and after granular activated carbon filtration at public water systems in Little Hocking, Ohio and Lubeck, West Virginia

Status report: Relationship of perfluorooctanoic acid (PFOA) and perfluorooctane sulfonate (PFOS) with pregnancy outcome among women with elevated community exposure to PFOA

March 18, 2009

Below is a link to a status report filed with the Wood County Court, summarising results of analyses linking C8 exposure in the Mid Ohio valley to markers of immune status. The reports are concise summaries of some results of this work. These results were also presented at a workshop at the annual conference of the Society of Toxicology - in Baltimore on March 19 by Science Panelist Tony Fletcher. More detailed reports are being submitted to peer-reviewed journals for publication. Right-click on the title and save or open the document (pdf format).

Status Report: PFOA and immune biomarkers in adults exposed to PFOA in drinking water in the mid Ohio valley

January 27, 2009

Below is a link to a Status Report submitted to the Wood County Court in Parkersburg West Virginia under the C8 Settlement. It is a concise summary of some results of this work. A more detailed report is being submitted to a peer-reviewed journal for publication. When it is accepted and published, details for accessing them will be provided here. Right-click on the title and save or open the document (pdf format). This report arises from work in one of the Science Panel studies "Cholesterol, diabetes, uric acid, and C8 levels among participants in the C8 Health Project"

Status report: Association of perfluorooctanic acid (PFOA) and perfluoroctanesulfonate (PFOS) with uric acid among adults with elevated community exposure to PFOA (pdf opens here)

October 15, 2008

Below are listed 3 Status Reports submitted to the Wood County Court in Parkersburg West Virginia under the C8 Settlement. Each report is a concise summary of the key findings of this work. More detailed reports are being submitted to a peer-reviewed journal for publication. When they are accepted and published details for accessing them will be provided here. Right-click on the title and save or open the document (pdf format). These three reports arise from work in one of the Science Panel studies "Cholesterol, diabetes, uric acid, and C8 levels among participants in the C8 Health Project"

  1. Status report: Factors associated with PFOA levels in a community surrounding a chemical plant
  2. Status report: Association of perfluorooctanic acid (PFOA) and perfluoroctanesulfonate (PFOS) with lipids among adults in a community with high exposure to (PFOA)
  3. Status report: A Cross-Sectional Analysis of Type II Diabetes in a Community with Exposure to Perfluorooctanoic acid (PFOA)
    [Note this status report "Status_Report_C8_and_diabetes_Nov2008.pdf" replaces the earlier one "Status_Report_C8_and_diabetes_Oct2008.pdf" which should be discarded as no longer current. There are some minor corrections. The interpretation and conclusions are unchanged.]

Procedure for release of Study Results

The Science Panel is planning to complete a series of reports on various health measures and C8 over the coming months and years that will contribute important knowledge regarding the potential health effects of C8 exposure. We explain here our process for making available these results: to the Court, to the public and the media, and though scientific journals. For a number of these results we are working in collaboration with West Virginia University When we complete the analysis and interpretation of the data on a specific issue, the following will occur:

  1. We will prepare a summary of our findings for the Court and a general audience, and that document will be submitted to the Court and posted here on the Science Panel website once the Court has received it.
  2. We will make ourselves available to respond to requests from the media regarding the implications of our findings or other issues of interest.
  3. We will prepare a detailed scientific report on the same results, that includes detailed information on the study and its findings for a scientific audience and submit that paper for review and publication by a medical/scientific journal. When the publication is accepted and published we will include a link here so people can locate the full text. We will be able to respond to further press queries at that time.
  4. In addition, we will come to the mid-Ohio Valley periodically to meet with interested groups to present and discuss our findings and interpretation in person.

It should be noted that this only concerns release of results from individual studies, not the announcement of the Science Panel's Findings regarding a probable link between C8 exposure and any disease. Reports on conclusions by the C8 Science Panel on whether or not there is a probable link with C8 for a number of diseases are submitted to the Court and posted on this website; follow the link on the left. This is explained on another page on this website: click on "The Science Panel" on the menu.

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